Allogeneic Stem Cell Transplantation (Current Clinical by Mary J. Laughlin, Hillard M. Lazarus

By Mary J. Laughlin, Hillard M. Lazarus

Across the world famous physicians and researchers assessment either the fundamentals of allogeneic stem telephone transplantation and up to date advances within the box, rather as they relate to antitumor results and graft-versus-host disorder additionally they offer specific decision-tree analyses to lead clinicians in picking out and dealing with their allogeneic transplant sufferers. The techniques mentioned hide numerous components, starting from stem cellphone mobilization in general donors, to symptoms for allogeneic transplantation except hematologic malignancies, to using nonmyeloablative conditioning regimens. The authors additionally discover new advancements within the optimum number of unrelated allogeneic grafts (e.g., matched unrelated donor, in part mismatched friend, or umbilical twine blood), the use allogeneic peripheral blood stem phone vs marrow-derived grafts for transplantation, and the kinetics of immune reconstitution after transplantation.

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In: Thomas ED, Blume KG, Forman SJ, eds. Hematopoietic Cell Transplantation, 2nd ed. Blackwell Science, London, 1999, pp. 168–175. 48. Stein AS, Forman SJ. Autologous hematopoietic cell transplantation for acute myeloid leukemia. In: Thomas ED, Blume KG, Forman SJ, eds. Hematopoietic Cell Transplantation, 2nd ed. Blackwell Science, London, 1999, pp. 287–295. 49. Miller CB, Rowlings PA, Zhang MJ, et al. The effect of graft purging with 4-hydroperoxycyclophosphamide in autologous bone marrow transplantation for acute myelogenous leukemia.

Biol Blood Marrow Transplant 2002;3:145–154. 72. Deeg HJ, Shulman HM, Anderson JE, et al. Allogeneic and syngeneic marrow transplantation for myelodysplastic syndrome in patients 55 to 66 years of age. Blood 2000;95:1188–1194. 28 Part II / Disease Indications: Allogeneic Transplantation Chapter 3 / Stem Cell Transplantation for ALL 3 29 Allogeneic Stem Cell Transplantation for Adult Acute Lymphoblastic Leukemia Partow Kebriaei, MD and Wendy Stock, MD CONTENTS INTRODUCTION PROGNOSTIC FACTORS IN ADULT ALL ALLOGENEIC TRANSPLANTATION FOR HIGH-RISK ALL DURING FIRST CR ALLOGENEIC TRANPLANTATION BEYOND CR1 USING HLA-IDENTIFIED SIBLING DONORS PRIMARY REFRACTORY ALL PHILADELPHIA CHROMOSOME-POSITIVE ALL FACTORS INFLUENCING TRANSPLANT OUTCOME LONG-TERM COMPLICATIONS OF ALLOGENEIC TRANSPLANTATION NOVEL TRANSPLANT APPROACHES REFERENCES 1.

N Engl J Med 1988;318:76–81. 28. Popplewell L, Forman SJ. Allogeneic hematopoietic stem cell transplantation for acute leukemia, chronic leukemia, and myelodysplasia. Hematol/Oncol Clin North Am 1999;13:987–1015. 29. Estey EH, Shen Y, Thall PF. Effect of time to complete remission on subsequent survival and disease-free survival time in AML, RAEB-t, and RAEB. Blood 2000;95:72–77. 30. Tallman MS, Rowlings PA, Milone G, et al. Effect of postremission chemotherapy before human leukocyte antigen-identical sibling transplantation for acute myelogenous leukemia in first complete remission.

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