Advances in microfluidics by Ryan T Kelly

By Ryan T Kelly

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2007). Stretching single molecular DNA by temperature gradient, Appl. Phys. Lett. 91: 154104. APL/91/154104/1 Jonáš, A. & Zemánek, P. (2008). Light at work: the use of optical forces for particle manipulation, sorting, and analysis, Electrophoresis 29: 4813–4851. , Steffen, P. & Fischer, T. M. (2002). Migration of a droplet in a liquid: effect of insoluble surfactants and thermal gradient, J. : Condens. Matter 14: 4823–4828. org/0953-8984/14/i=19/a=309 Kim, H. S. & Subramanian, R. S. (1989a). Thermocapillary migration of a droplet with insoluble surfactant: I.

Laser switching and sorting for high speed digital microfluidics, Appl. Phys. Lett. 92: 154105. , Magome, N. & Yoshikawa, K. (2004). Forward and backward laser-guided motion of an oil droplet, Phys. Rev. E 70: 046301. , Tsukita, S. & Funatsu, T. (2006). On-chip cell sorting system using laser-induced heating of a thermoreversible gelation polymer to control flow, Anal. Chem. 78: 695–701. , Chen, D. L. & Ismagilov, R. F. (2006). Reactions in droplets in microfluidic channels, Angew. Chem. Int. Ed. 45: 7336–7356.

A gas bubble is formed in the liquid phase, and a heating laser beam is focused in the liquid just behind the bubble. By slightly increasing the temperature at the rear of the bubble, the laser induces evaporation and the vapor then condenses at the front interface. This leads to a net fluid transfer across the bubble. The authors then applied this method to the distillation of a dye solution, the transferred solution being dye-free while the fluorescence enhancement can be observed in the untransferred one.

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